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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfec5e2f895061eb1938841aa3027c63729ef2e4d660d16977d6691cc25f179' 
  AND token = 'LWGnNClx7/EO7rLjEutDqyCimBZJwYBNJ8+A7EdiRlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}