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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a144ef1b437168318430a67db86dc8192df3a1650aeaf488815e4185b79df962' 
  AND token = '0VsbdFN1jX51zDJ8XasbK5fHnIzOCu+2HpqaQtkM4Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}