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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75caf7a3e7cd166ebfb9ce9ce6b27a0e173a66889cae18a6a8c7a49b0c5fc8d0' 
  AND token = 'B6ITXfL9ABHZJa4qGqHz7kF3YtFWo8EqQGXHOkfrsMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}