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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6463852e7647e5542eaedad445496bfb113112f2e5e424f17d1ca60142cd7bea' 
  AND token = 'qYveNurUUS9qtAGcgUfV/qk+yoWWFvV4NUOfHOWAcno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}