SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529174be096d3a50982e663015e957735d147bae1f04833a22777ee3a4c11230' 
  AND token = 'p1mM2quaTrKfL+vkHyZLY1V57wi3B3oR6lrzVqiowmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}