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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7997bc67ab9138cf0116f969ddfab673c664f979f4da3cd34fcf176d02fd095' 
  AND token = 'eF8IkbqNso7pvYD4U9DB/ACOseK8Z4TNv23ZRjZdyj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}