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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae09918fe3614f3042f49297238ea9693aa5e9ac96c65b7de35daf222b3a806' 
  AND token = '/RWrLQh9+cVKXSyYAcizAewKmWEeK6Y094XVRcOVZAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}