SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4e64b13265e3a00afeea88e07f5949a7b131b17143eb66846dc9df5086cd02' 
  AND token = 'Lq/gZBVNdwFk3Myeu6upnTFMtN1WRsMBgHIlGxMA9h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}