SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26ca766f1623f76df093a98e08af4b6d6eb22e1aeaded1133dfcd68f7431ed0' 
  AND token = 'jPUneYL+MKe/HAK/Kank4mjlkUlh/796TsQ2Iiqb1CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}