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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270c15dc130f487aa9ec04aa889aa37ee7a4a2e2002a1617b7bad579351c4498' 
  AND token = 'N4FG0obgLsYhiS2OVnlYd2yDrfQxuN4rBtUsEqEwjr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}