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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a5b39e578a4c99a45bba5b1fa530fe6fe9775fe391fa42b2b6038881e43e65' 
  AND token = 'EHbpKw/BIILJ4PB+aFhWEoimmUypttGZ/eeQxjCuIpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}