SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9477700727a3a53e04efbeb92927f4f07811051fd0963ce00bc72a8f7f84890f' 
  AND token = 'hDTi4dJrXrkeFVzaQXJkCkNcI2DZqDyGVAsCmMq5Yho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}