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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05268e3453008833077d120e706a48d960010e7d01044f793db3b6c9c3ca8b97' 
  AND token = 'x2RYP349ZmhVTkE53vWlG7JLprh9iTTJhFNykLIhBhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}