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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7121181933c2d9f877a51defced386c73fdf3ec2c1b8fe700e7f3525c78185c4' 
  AND token = 'GcyagOrt3qD2J0srsuE17CHjAwrpinAmyEDu91nuYQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}