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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc70536fee92dcf3c9812c73c81f2b99c8b7fbace351dd39f9b87deaa9980a3' 
  AND token = 'UwiOxRmb/sO7HqhvGvJ+nUf3+tLdl+XbYP76O5RC6Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}