SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4347f810f4b06d12829e8e70ba5765f555e848ed4d5fd1dfc443e2a784786aad' 
  AND token = 'K5cI+XucXgBrKKNRolDFG5PqflNA59IlYC33X9SYEm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}