SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e3e2507bd58272efd0eebd7d163632b09253ee5bd721640a1b1fb797e48d27' 
  AND token = 'sy/wf/EmTRWbZJk7wlFvSdtq90KiUQO5jI3NpSrB+UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}