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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbe317c5f417e8c9b13a1ced4ee0e86f9f12346c5c370985adafaa9a7738870' 
  AND token = 'u7utNAZ1JK0xjfX6Nvsuxdw+eUuEwUDr79DTvfdGJmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}