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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135dcd0054dcbc8e3173294ff97182b01843d2424773f14a4e51fda3024ceaa5' 
  AND token = 'YGqKuyOkHWQbMuAl0f+fqWxZ6LCpAu5VQbNvRoU18QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}