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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f615da970a8aba90ae15db349098896c2be8540e6b021347a05abc6bc56b7ad' 
  AND token = 'ZPE17SIlS5GtB+983VnNQf/wF7v9uyUBbTKzY5MuPNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}