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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f378cc4fff5260e10d967de85209e0475ffa7618e69fc4fb3e063d733d0be6d1' 
  AND token = 'onW5jkAAjIzJ7vuqVYRq10pMP8cXR1SVQ+qH6fwHZII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}