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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c269fa8cedef11eb84fbb598777ba8a762166e231956aba123767c86593c80b' 
  AND token = 'xmwL2R+SPudW9K1d8X2fdgLg/0A8sDfMKQFwHJD9Cng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}