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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589035200ef20df6ab1791db6504b4cfc4901c3a6ac13cc0dfeabb82ebf07f44' 
  AND token = 'wRwwNS0LEtgUODlTNg4YdfgVVqZa82+b+AZyTu7gepk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}