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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d1fa8042edc283ec00a97d00d7b081b829f5f66aa050fb6005398d56b90a9e' 
  AND token = '2Q73u7/hd3mL5CjU5mtvGawsELxzFB4T45AKpfK4ZiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}