SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b889ad651921de757b035226fbc148ee7620967dd83b4c908774722afd9a1b' 
  AND token = 'e3ZW88Yk5TwSrfj2/B4DBHlmSCVTQqzs+2sO+WkCNNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}