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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64289ab58c7a66a6246b7213cf6bbad80994ba50c9b5ec1456740ce14a998e07' 
  AND token = 'RrhzLNAO3XnLE88hy/lturQ795vy56TZIxJXRjUlKPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}