SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34380dec54b2c04bba8ee8acf68676f2fed4e591e5bca0dec52e8ba47f450af4' 
  AND token = 'SLT54ZkuYGXawtr/r2OVwM7RRSQ5+JYBU/PF31qlOsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}