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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36cd34bc56ae91fc0587f52da5ee52669450d929382ac7a5391854ca5e079320' 
  AND token = 'Hdjn8ocVY9Ak9XA/ernpo+q0NtEHYa4y0l0wmchYHOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}