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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751fe827ed7d70162f3f6755d121a596e4a802e33279c7edd0a60fc8f9281a51' 
  AND token = 'AvLTSveVPo4K1AojuF9V4y1jRH10G0rIkGHKOO/5nKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}