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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3556b0b2710c6aade7699ff3f8caaeb848cff278c904a1a93f5d1258c2050948' 
  AND token = 'Q4pGQ8e4yG5K43/iMHcINXxLIopcwZhTLHhI/ezXOIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}