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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7080da01e04c28473f201e3e1afc695cb57cf512ab448c70951926c8cf39b3' 
  AND token = 'TX7rH0CwODgAmOAN2/uJ0tmL3hJFXkPkG9uZigYEpgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}