SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b478b4ea5c9939d4a87c8f4a49257cf16f52ef537355a6bc7a984fe29967d4' 
  AND token = '+haKWoQqvjLYVIlsKMC5qv+1A7i9QfcFd9Q7Jy5wdY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}