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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1659aa3a008bd2456843c8dd0f1a2dd6c487cd195c31bea242d2dfd8e4aee5fd' 
  AND token = 'C3Bx7iEA5vWXAFXp3+iX6S2+V+mAEnlqlgFGO7Cvyho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}