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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c08ab5907319918a908cf3dc6803cf8be7eb634e5fd49e74f621342990ce652' 
  AND token = '6HG2RJGKALYXz1SHW44HDHcRSVz/H2VW+70dKAZu7+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}