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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb3aea72f5c59d1c55fe68bbc7328a29b68c2dd20abbc63930ee47a0dc8008f' 
  AND token = 'Btf8VWBWv/lXUMrbszRHiPEsCt29Ztm1kVpJGaJfWIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}