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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca46d5a61942dd6bdf918861bcd8e0fc382c8506880be1369e008fdb595da7e' 
  AND token = 'x4dJ47JZb1S3j78YSdHHR/kk+nBMTXXUFTWyACQ8t1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}