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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3a64334e123ce06a48edbe1348f058b62d6191ff0c1e5258a9535edea70d0ba' 
  AND token = '4brPNL12Oh4fVV49HnI7sakw4TwL0DqAe4BdbonHrI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}