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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9257c847c2c66f8f23c967df596ff7298e78253fbfed7f2bfee1d62541cadbbd' 
  AND token = 'kRupUqApgjCEB2TB2p3SRp+preV4xLq8oNZBuFXVcAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}