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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72dbd0faaa2ac1830b0a68e46fd4f1b94bca274f901c559bf04dac9f67c9ee19' 
  AND token = 'gxKzuhj5h54sMmSq3KhX2MPuvYP0xZnqfUeESWEqIOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}