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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b508e73c21086c7397b289c6283823cc0f2c1071b94af21bac6e71b68694a7' 
  AND token = 'iqSPG5M76kO1F1jUHcpkfRFipxt2cFvlYxBq8cVA5U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}