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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41071f9128561ba6163af888be4b2af38ee8b68b6f4e3abe9ef50e8757fc306' 
  AND token = '6jJYGGYmZzm0L1bqrOEAx94fg1Nzn2BTrN6D+xJb9lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}