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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c4feb865d56544aa79261ddafffe24ea7e376c17c4c1a6f6d68abafb99648a0' 
  AND token = 'qnqU1ouiIdshSBO3eaRTg1KkpNKxnZnm4M7jso1AeaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}