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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b41d6b1c5fbb31cc742ed1cc65726a08e525547b8083658548a8eaef2c8507' 
  AND token = 'xtzd8Sqy/J4w8DpLQ28S6puxxsKoTlh2aq24JGy9NsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}