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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd245d467e1e35d3503a64f1d98d2d95136a7f3b023d530e47a1e96979bc31743' 
  AND token = 'Kp+G7B8QOhD/qMp8gyT3HHoxxvdLE4P4jPLF2NWbDcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}