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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a62d7eb560a75e898a7dc8df40d7a21a90b08e1febd1ad857e503f110be1d27a' 
  AND token = 'DmaM0d4XI3941kIWYBxGaSjpX2oEn5jXWoTJXmMpdgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}