SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04df2db73fcad9724f4dc8fe084e17a911213bf49d69d2ba14b9a0adae863320' 
  AND token = 'YEthiIhebuGJEoGPPP9r1BtBITbxsK+5Su7OyDhp+6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}