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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4743bdd1b1aa7310b2e7412572b0ee3f95296c7607a6af20c90b8a98255eb3b9' 
  AND token = 'wEBTpHz8/AP9hbleb31O+ivEEenYH/LdV3C7gxrB8Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}