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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75cea099c37c21f7d7532452ed8b27da980ba2af9ed0a44124f617d56b48c46d' 
  AND token = 'y6fr9NuR9/HhmMGW8eCoxnKbf6WqU6s0XLusImu+qeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}