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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d2bcc045c593de770922e295c701453d2a4d2f1d017df84a935e559bb62173' 
  AND token = 'Wd3/BIE61w46ULhiEjwz1kcC5C2pKB0Hs8QG1z6d7Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}