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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b456d1f7b262fdfee6f93f2250d27a37e5bee04229682e04174793adf8deb217' 
  AND token = 't6abZ8udtMyJeMTiqkdnScXzxo5aHDn738w5rP8Qo30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}